ACOG Alpha Cognition Inc. Insider Trading

Opaleye Management buys 73,738 shares for $434,713.77 at $5.90 avg; 10% holder now holds 2,604,107 shares

Opaleye Management Inc, a 10% owner, executed 3 separate purchases totaling 73,738 shares for $434,713.77 between May 27–29, 2026, at a blended average price of $5.90. The current price of $6.19 sits -46.4% from the 52-week high of $11.54, within the 52-week range of $4.50–$11.54. Opaleye's track record across all tickers shows 16 prior open-market buys with an average 90-day return of +8.3% and a 90-day win rate of 100.00%, while at ACOG specifically, all 5 prior buys (most recent on 2026-05-21, 2026-05-20, 2026-05-18, 2026-05-15, and 2026-03-30) were well-timed at the 90-day mark. However, the company reported negative net income of $-6,478,018.00 in its latest quarter and was unprofitable over its most recent full fiscal year, which provides material context for evaluating the investment signal embedded in this accumulation.

10% owner Opaleye Management buys 24,376 shares in 2 transactions for $140,545.09; stock down 49.3% from 52-week high.

Opaleye Management, a 10% shareholder, acquired 24,376 shares across two separate purchases on 2026-05-20 and 2026-05-21 at blended average price $5.77, bringing holdings to 2,530,369 shares post-transaction. This accumulation occurs while the stock trades -49.3% from its 52-week high of $11.54 and has declined 16.3% over the prior 30 days. At ACOG specifically, Opaleye's 5 prior trades show a timing pattern where 4 of 5 buys achieved positive 90-day returns, including three consecutive March purchases returning +17.7%, +35.0%, and +29.7% at the 90-day mark. Against this backdrop, the company remains unprofitable with net income of $-6,478,018.00 against quarterly revenue of $3,533,798.00. The filing provides raw transaction and position data; investors should assess whether the insider's historical accuracy at this ticker and the magnitude of accumulated shares signal continued conviction or reflect other factors in a loss-making business.

Opaleye Management Inc (10% owner) buys 34,043 shares at $5.76 avg; prior 5 ACOG trades all 90d positive, now at 52-week low -49.7%

Opaleye Management Inc executed 2 separate purchases totaling 34,043 shares for $196,009.03, adding 1.4% to a 2.51M-share position. The stock trades at -49.7% from its 52-week high of $11.54 and is down -16.4% over the past 30 days, despite a +0.0% 90-day change. Notably, this insider's prior 5 purchases at ACOG (March 24–30, 2026) all showed positive 90-day returns ranging from +6.4% to +19.3%, establishing a pattern of well-timed entry at this ticker. The current purchases occur at prices ($5.83 and $5.69) near the lower end of the 52-week range ($4.50–$11.54), following a sharp recent decline. However, the company remains unprofitable (net income $-6,478,018.00 for the most recent period) with a market cap of $126,289,803.20, adding material context to the timing and scale of this accumulation.

COO D'Angelo Lauren purchases 3,500 shares of ACOG at $5.76 amid -49.7% drawdown from 52-week high; holdings now 140,695 shares.

D'Angelo Lauren, Chief Operating Officer, purchased 3,500 shares at $5.76 on 2026-05-19, increasing holdings to 140,695 shares. The purchase occurs at a significant discount to the 52-week high of $11.54 (currently -49.7% from peak), and the stock has declined -16.4% over the past 30 days and is flat over 90 days. The company is unprofitable, reporting net income of $-6,478,018.00 for its most recent full fiscal year against quarterly revenue of $3,533,798.00, creating substantial execution risk. While insider purchases are often monitored as signals, the buy occurs within a context of material losses, declining share price momentum, and a market cap of $126,289,803.20 where the insider's new 3,500-share accumulation represents a modest 2.6% increase to existing holdings. The combination of financial deterioration and deep valuation discount warrants investor scrutiny of whether the purchase reflects confidence in operational turnaround or simply activity at depressed levels.