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ACOG Alpha Cognition Inc. Insider Trading

Latest: Insider Bought $435K of Shares · May 2026

Multiple insiders have been active at Alpha Cognition Inc. (ACOG): 6 distinct insiders account for 23 buy filings and 0 sell filings as of Jun 2026. Its highest-significance filing in the last 90 days: Opaleye Management Inc bought $435K, transaction dated May 2026.

23 filings analyzed · Latest 2026-06-29

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Buys
23
Sells
0
Insiders
6
Direction
Net buying

Alpha Cognition Inc. leadership

CEO
Henry Du — CHIEF EXECUTIVE OFFICER
CEO
Michael McFadden — CHIEF EXECUTIVE OFFICER
COO
Lauren D'Angelo — Chief Operating Officer
Chair
Dr. Robert Wills — non-executive Chair of the Board

Historically, high-priority insider buys have outperformed the S&P 500 by a median ~2% over the 30 days after the trade — the edge is concentrated in that first month (n ≈ 5,579, 2024-2026). Past results don't predict the future. How we measure this ↗

June 2026
2026-06-29
high
152,533 shares
$976,490
@ $6.40
Significance 6

Opaleye Management acquired 152,533 shares at blended avg $6.40 in 2 purchases, raising stake to 2.81M shares (+5.8%)

Opaleye Management, a 10% owner of Alpha Cognition Inc., executed 2 separate purchases totaling 152,533 shares for $976,489.87 on June 25-26, 2026, at an average price of $6.40. The stock currently trades at $7.89, representing a 30-day gain of +27.7% and a 90-day gain of +31.9%, though it remains 31.6% below its 52-week high of $11.54. The company remains unprofitable with a net loss of $6,478,018.00 in the latest quarter. Five prior buys by this insider at ACOG within days of this filing (June 9-15) lack measurable outcome data yet. Across Opaleye's cross-ticker history, prior buys averaged +13.0% 30-day returns, though the timing quality of same-ticker purchases cannot yet be assessed.

2026-06-15
high
7,685 shares
$45,773
@ $5.96
Significance 7

10% owner Opaleye Management acquires 7,685 shares over 3 days (June 11–15) at $5.96 avg; company unprofitable, stock down 48.1% from 52-week high.

Opaleye Management, a 10% shareholder in unprofitable ACOG, executed 3 separate purchases totaling 7,685 shares for $45,773.11 over a narrow four-day window from June 11–15, 2026, at a blended average price of $5.96. This accumulation occurs within a challenging valuation context: the company posted $-6,478,018.00 in net income on $3,533,798.00 quarterly revenue, and the stock trades at $5.99 today, 48.1% below its 52-week high of $11.54. Notably, Opaleye's prior 5 trades at ACOG (all buys on May 20–29) were each well-timed at the 90-day mark, with returns ranging from +2.0% to +5.6%, establishing a consistent pattern of entry execution at this ticker. The timing of this latest purchase cluster shortly after those successful May positions, combined with the continued accumulation despite material losses in the latest quarter, warrants attention to whether management commentary or operational developments informed this insider activity.

2026-06-11
high
30,728 shares
$183,692
@ $5.98
Significance 7

Opaleye Management (10% owner) purchases 30,728 shares in ACOG for $183,691.91; stock up 10% in 30 days despite -47.7% from 52-week high.

Opaleye Management acquired 30,728 shares across two separate transactions for $183,691.91 at an average price of $5.98, increasing holdings by 1.2% to 2,644,889 shares. This accumulation occurs while the stock trades 47.7% below its 52-week high of $11.54, though it has gained 10% over the prior 30 days. Notably, Opaleye's prior 5 purchases at ACOG were all well-timed, with positive 90-day returns ranging from 2.0% to 5.6%, establishing a consistent pattern of favorable entry points at this ticker. Against this backdrop, the company remains unprofitable with net income of $-6,478,018.00 over its most recent full fiscal year and quarterly revenue of only $3,533,798.00, leaving limited fundamental support for the stock's valuation despite the 10% near-term recovery.

2026-06-09
high
10,054 shares
$58,596
@ $5.83
Significance 7

10% owner Opaleye Management buys 10,054 shares of ACOG at $5.83; stock down 48.0% from 52-week high but insider has 5 consecutive buy-side wins at this ticker.

Opaleye Management, a 10% shareholder, purchased 10,054 shares at $5.83 on 2026-06-05, expanding its position to 2,614,161 shares. The transaction occurs with Alpha Cognition trading at $6.00, down 48.0% from its 52-week high of $11.54, despite the company reporting net income of $-6,478,018.00 for its most recent period. Notably, all 5 prior purchases by this insider at ACOG showed positive 90-day returns, ranging from +2.0% to +5.6%, establishing a 100.00% well-timed rate at the 90-day mark on this ticker. The cross-ticker track record shows 16 prior buys with an average 90-day return of +11.4%, providing broader context for the insider's historical buy-side timing, though this ticker-specific pattern at ACOG represents the most directly comparable precedent.

May 2026
2026-05-29
high
73,738 shares
$434,714
@ $5.90
Significance 7

Opaleye Management buys 73,738 shares for $434,713.77 at $5.90 avg; 10% holder now holds 2,604,107 shares

Opaleye Management Inc, a 10% owner, executed 3 separate purchases totaling 73,738 shares for $434,713.77 between May 27–29, 2026, at a blended average price of $5.90. The current price of $6.19 sits -46.4% from the 52-week high of $11.54, within the 52-week range of $4.50–$11.54. Opaleye's track record across all tickers shows 16 prior open-market buys with an average 90-day return of +8.3% and a 90-day win rate of 100.00%, while at ACOG specifically, all 5 prior buys (most recent on 2026-05-21, 2026-05-20, 2026-05-18, 2026-05-15, and 2026-03-30) were well-timed at the 90-day mark. However, the company reported negative net income of $-6,478,018.00 in its latest quarter and was unprofitable over its most recent full fiscal year, which provides material context for evaluating the investment signal embedded in this accumulation.

2026-05-22
high
24,376 shares
$140,545
@ $5.77
Significance 7

10% owner Opaleye Management buys 24,376 shares in 2 transactions for $140,545.09; stock down 49.3% from 52-week high.

Opaleye Management, a 10% shareholder, acquired 24,376 shares across two separate purchases on 2026-05-20 and 2026-05-21 at blended average price $5.77, bringing holdings to 2,530,369 shares post-transaction. This accumulation occurs while the stock trades -49.3% from its 52-week high of $11.54 and has declined 16.3% over the prior 30 days. At ACOG specifically, Opaleye's 5 prior trades show a timing pattern where 4 of 5 buys achieved positive 90-day returns, including three consecutive March purchases returning +17.7%, +35.0%, and +29.7% at the 90-day mark. Against this backdrop, the company remains unprofitable with net income of $-6,478,018.00 against quarterly revenue of $3,533,798.00. The filing provides raw transaction and position data; investors should assess whether the insider's historical accuracy at this ticker and the magnitude of accumulated shares signal continued conviction or reflect other factors in a loss-making business.

2026-05-19
high
34,043 shares
$196,009
@ $5.76
Significance 7

Opaleye Management Inc (10% owner) buys 34,043 shares at $5.76 avg; prior 5 ACOG trades all 90d positive, now at 52-week low -49.7%

Opaleye Management Inc executed 2 separate purchases totaling 34,043 shares for $196,009.03, adding 1.4% to a 2.51M-share position. The stock trades at -49.7% from its 52-week high of $11.54 and is down -16.4% over the past 30 days, despite a +0.0% 90-day change. Notably, this insider's prior 5 purchases at ACOG (March 24–30, 2026) all showed positive 90-day returns ranging from +6.4% to +19.3%, establishing a pattern of well-timed entry at this ticker. The current purchases occur at prices ($5.83 and $5.69) near the lower end of the 52-week range ($4.50–$11.54), following a sharp recent decline. However, the company remains unprofitable (net income $-6,478,018.00 for the most recent period) with a market cap of $126,289,803.20, adding material context to the timing and scale of this accumulation.

2026-05-19
high
Chief Operating Officer
3,500 shares
$20,160
@ $5.76
Significance 6

COO D'Angelo Lauren purchases 3,500 shares of ACOG at $5.76 amid -49.7% drawdown from 52-week high; holdings now 140,695 shares.

D'Angelo Lauren, Chief Operating Officer, purchased 3,500 shares at $5.76 on 2026-05-19, increasing holdings to 140,695 shares. The purchase occurs at a significant discount to the 52-week high of $11.54 (currently -49.7% from peak), and the stock has declined -16.4% over the past 30 days and is flat over 90 days. The company is unprofitable, reporting net income of $-6,478,018.00 for its most recent full fiscal year against quarterly revenue of $3,533,798.00, creating substantial execution risk. While insider purchases are often monitored as signals, the buy occurs within a context of material losses, declining share price momentum, and a market cap of $126,289,803.20 where the insider's new 3,500-share accumulation represents a modest 2.6% increase to existing holdings. The combination of financial deterioration and deep valuation discount warrants investor scrutiny of whether the purchase reflects confidence in operational turnaround or simply activity at depressed levels.

March 2026
2026-03-31
high
11,850 shares
$60,018
@ $5.06
Significance 6

Opaleye Management (10% owner) purchases 11,850 shares across 2 transactions for $60,018.51 at $5.06 average amid -51.2% decline from 52-week high.

Opaleye Management executed 2 separate purchases totaling 11,850 shares for $60,018.51 at a blended average price of $5.06, increasing its holding to 2,471,850 shares. The timing coincides with significant recent price weakness: the stock is -51.2% from its 52-week high of $11.24 and down 8.5% over the past 30 days. Alpha Cognition remains unprofitable with negative net income of $-1,318,074.00 in its latest quarter. Opaleye's prior trades at this ticker are all recent buys (5 consecutive buys from 2026-03-18 through 2026-03-26), but their 90-day outcomes remain immeasurable; across the insider's broader cross-ticker track record, 16 prior buys vs 4 prior sells suggests a historical bias toward accumulation, though this context does not speak to timing accuracy at this particular security.

2026-03-26
high
20,082 shares
$108,631
@ $5.41
Significance 6

10% owner Opaleye Management buys 20,082 shares across 3 days for $108,630.97 at blended $5.41, amid -11.2% 30-day decline and ACOG unprofitability.

Opaleye Management Inc., holding 2.46M shares (10% ownership), executed 3 separate purchases totaling 20,082 shares for $108,630.97 between 2026-03-24 and 2026-03-26 at prices ranging from $5.28 to $5.59, averaging $5.41 per share. The timing is notable: the stock has declined 11.2% over 30 days and 14.8% over 90 days, trading at $5.34 (current), down 52.5% from its 52-week high of $11.24. The company is unprofitable, with latest-quarter net income of $-1,318,074.00 on revenue of $2,840,858.00. Opaleye's recent trading pattern at ACOG shows 5 consecutive buys over 6 trading days (2026-03-12 through 2026-03-19), with this 3-transaction filing following immediately. The prior purchases' 90-day outcomes are not yet measurable. The sustained buying during a multi-month downturn, combined with the insider's 16 prior cross-ticker buys versus only 4 sells, establishes a strong acquisition posture, but the company's negative profitability and the stock's steep declines warrant scrutiny of the underlying fundamentals driving these purchases.

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