Emily M. Leproust

TWST CEO Emily Leproust sells 16,470 shares for $1,118,554.58 via scheduled 10b5-1 plan; retains 846,872 shares + 75,439 options.

Emily M. Leproust, TWST CEO, executed 4 separate open-market sales totaling 16,470 shares for $1,118,554.58 on 2026-05-28 under a pre-arranged 10b5-1 trading plan adopted 2025-05-27. Prices ranged from $65.33 to $68.61 (blended average $67.91), near the current price of $67.86 and well above the 52-week low of $23.30. This is a 1.9% reduction of her non-derivative holdings, leaving her with 846,872 shares post-transaction. The sale follows modest near-term stock strength (+12.4% over 30 days, +45.5% over 90 days) but occurs at a company trading 4.5% below its 52-week high of $71.04. TWIST remains unprofitable (latest quarter net income $-44.0M) despite revenue growth of +20.3% year-over-year and latest quarterly revenue of $110.7M. Her prior sales at TWST have shown mixed near-term results (30-day returns: -8.2%, -7.2%, -9.5%, +1.8%, -2.1%), and her cross-ticker track record shows average 90-day return of +7.5% after sells. The scheduled nature of this sale under her 10b5-1 plan means the timing reflects pre-planned portfolio management rather than a discretionary decision responding to current conditions.

TWST CEO Emily Leproust sold 49,299 shares for $3,213,653.17 via 10b5-1 plan; retains 846,872 shares plus 208,835 option holdings.

CEO Emily M. Leproust executed 3 separate sales totaling 49,299 shares for $3,213,653.17 (blended average price $65.19) on May 26–27, 2026, as part of a pre-arranged 10b5-1 trading plan adopted on 2025-05-27. This is a scheduled, non-discretionary transaction. Post-sale, she retains 846,872 non-derivative shares and 208,835 shares in derivative holdings (option pools), representing a -5.5% reduction in her non-derivative position. The current price of $69.03 is above the sale prices ($65.08–$66.28), reflecting a 16.7% gain in the stock over the past 30 days and +47.1% over 90 days. While her prior sales at TWST show mixed results (three recent sells in April 2026 followed by 30-day declines of -8.2%, -7.2%, and -9.5%), the structured nature of the 10b5-1 plan removes discretionary timing from this decision and positions it as a pre-planned liquidity event. The company remains unprofitable (net income $-44.0M on latest full-year basis) despite 20.3% annual revenue growth.

CEO Emily Leproust sold 9,671 shares at $65.24 blended average; stock now $58.85 (-6.9% from 52-week high), company unprofitable.

Emily Leproust, CEO of unprofitable Twist Bioscience, executed 3 separate sales totaling 9,671 shares for $630,957.35 across April 21-22, 2026, at prices ranging from $65.01 to $66.00. The stock has since declined to $58.85, 6.9% below its 52-week high of $63.20, suggesting the CEO may have sold near a local peak. Her cross-ticker track record shows a 0.00% well-timed sell rate (0 of prior 4 sells preceded subsequent 90-day declines), and at TWST specifically, 0 of 4 prior sales were well-timed at the 90-day mark—a consistent pattern of selling into strength rather than before downturns. She retains 858,887 shares post-transaction, a modest 1.1% reduction from her 868,558 share position. The company reported negative net income of $-30,507,000.00 on quarterly revenue of $103,698,000.00, indicating structural profitability challenges that merit investor attention despite 20.3% annual revenue growth.

Leproust sold 31,379 shares of TWST at $31.44 on 2025-10-30; stock down 41.6% from 52-week high of $54.07.

Emily M. Leproust, CEO of Twist Bioscience, sold 31,379 shares for $986,690.69 at $31.44, reducing her holdings by 4.1% to 738,809 shares. The transaction occurs as TWST trades 41.6% below its 52-week high of $54.07, though the stock has recovered 14.7% over the past 90 days. Her prior two measurable sales at this ticker (November 2024 and October 2024) produced positive 90-day returns of 16.6% and 7.5% respectively, meaning the stock rose after both sales—a pattern that indicates poorly-timed exits from an upside perspective. The company reported positive net income of $20.4M in the latest quarter alongside 27.7% annual revenue growth, yet remains unprofitable on a full-year basis. This sale occurs just 24 days after her previous sale on 2025-10-06 at TWST, suggesting a deliberate series of dispositions rather than a one-off event.

Twist CEO Leproust sells 31,348 shares at $32.19; current price $32.79, down 39.4% from $54.07 high.

Leproust sold 31,348 shares (5.0% of pre-transaction holdings) on 2025-10-06 at $32.19, maintaining substantial holdings of 601,212 shares post-transaction. The sale occurred near the current price of $32.79, approximately 39.4% below the 52-week high, during a period of mixed momentum (30-day +24.9%, 90-day -14.8%). Reviewing her prior sales at Twist: a November 2024 sale showed 90d return of +16.6%, and an October 2024 sale showed 90d return of +7.5% — both instances where the stock subsequently rose after her sale, indicating neither trade was well-timed by sell-timing standards (0 of 2 prior TWST sales were well-timed). The company recently reported $96.1M quarterly revenue with +27.7% annual growth and $20.4M net income in the latest quarter, though the full-year basis remained unprofitable. The modest percentage of holdings sold and continued substantial retention suggests incremental portfolio adjustment rather than a pronounced conviction shift.

CEO Emily M. Leproust sold 14,334 shares of TWST at $44.60 on 2024-11-06 for $639,368.07; now holds 589,552 shares.

Leproust sold 14,334 shares at $44.60 during a period when TWST stock has recovered +9.5% over 30 days and +3.2% over 90 days, though it remains -22.9% below its 52-week high of $58.88. The sale reduced her holdings by -2.4% to 589,552 shares, representing a modest portfolio adjustment. The company generated $81.5M in quarterly revenue with +20.4% annual growth, but reported a net loss of $-85.6M and remains unprofitable on a full-year basis. Her prior TWST sell on 2024-10-02 saw a 30-day return of -3.8%, indicating the previous sale preceded near-term weakness, though the 90-day outcome for that trade is not yet measurable. The transaction occurred at a discount to the current price of $45.40, providing context but no forward signal of insider intent.

CEO Emily Leproust sells 13,605 shares of TWST at $43.21; retains 481,918 shares amid unprofitable operations.

CEO Emily Leproust sold 13,605 shares (13.6K shares) at $43.21 on 2024-10-02, leaving her with 481,918 shares (481.9K shares) post-transaction. The stock currently trades at $43.34, and the company reported a net loss of $-85,571,000.00 ($-85.6M) for its most recent full fiscal year despite generating $81,464,000.00 ($81.5M) in quarterly revenue. The CEO's substantial residual stake of 481,918 shares suggests material ongoing alignment with shareholder interests, and the modest sale of 13,605 shares represents a -2.7% reduction in her holdings. Given Twist's unprofitable status and negative trajectory on the 90-day change of -10.6%, the timing of a discretionary insider sale during operational challenges warrants investor attention, though the CEO's dominant retained position indicates she remains significantly exposed to company outcomes.