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ZLAB Zai Lab Ltd Insider Trading

Latest: Chair Sold $2.0M of Shares · May 2026

Multiple insiders have been active at Zai Lab Ltd (ZLAB): 3 distinct insiders account for 3 buy filings and 11 sell filings as of Jul 2026. Its highest-significance filing in the last 90 days: Chair Du Ying sold $2.0M, transaction dated May 2026.

14 filings analyzed · Latest 2026-07-06

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Buys
3
Sells
11
Insiders
3
Direction
Net selling

Zai Lab Ltd leadership

CEO
Samantha (Ying) Du — Chief Executive Officer
CFO
Yajing Chen — Chief Financial Officer
COO
Josh Smiley — Chief Operating Officer
General Counsel
F. Ty Edmondson — Chief Legal Officer
Chair
Samantha (Ying) Du — Chairperson of the Board of Directors
July 2026
2026-07-06 10b5-1 Plan
low
1,736 shares
$33,071
@ $19.05
Significance 4

Director Richard Gaynor buys 1,736 shares of ZLAB at $19.05 under pre-arranged 10b5-1 plan; stock -53.7% from 52-week high.

Richard Gaynor purchased 1,736 shares at $19.05 on 2026-07-01 as part of a 10b5-1 trading plan adopted on 2025-12-16, making this a scheduled transaction rather than a discretionary trade. ZLAB is trading at $19.08, approximately -53.7% from its 52-week high of $41.20, though the stock has gained 14.8% over the prior 30 days. The company remains unprofitable with a net loss of $-51.0M against revenue of $99.6M in the latest quarter, despite annual revenue growth of 15.3%. Gaynor's prior purchase at this ticker on 2026-03-17 showed similar post-purchase price action: +24.3% over 30 days followed by -6.2% over 90 days, which mirrors the recent 30-day gain and negative longer-term trajectory now visible in the current price context.

May 2026
2026-05-19 10b5-1 Plan
medium
Du Ying Sell
Chairperson & CEO
100,000 shares
$1,986,875
@ $19.87
Significance 6

CEO/then-Chair Du Ying sold 100,000 ZLAB shares for $1,986,875 via scheduled 10b5-1 plan; stock down 58.6% YTD, company unprofitable with $-51.0M net loss

Du Ying, who was Chairperson & CEO at the time of filing, executed 2 separate sales totaling 100,000 shares for $1,986,875.00 on May 15 and May 18, 2026 under a pre-arranged 10b5-1 trading plan adopted on 2025-11-11, reducing holdings by 8.2% to 1,122,626 shares. The sales occurred as ZLAB's stock trades at $18.37, down 58.6% from its 52-week high of $44.34, with 30-day and 90-day declines of 24.1% and 9.0% respectively, while the company reported negative net income of $-51,016,000.00 against quarterly revenue of $99,611,000.00. His prior 5 sales at ZLAB (March 2026) all showed positive 30-day and 90-day returns, contrasting with the steep post-transaction decline now underway. The scheduled-plan nature of this filing precludes timing characterization, but the backdrop of significant stock deterioration and persistent unprofitability warrants investor attention to the company's fundamental trajectory and capital allocation.

2026-05-15 10b5-1 Plan
medium
Du Ying Sell
Chairperson & CEO
100,000 shares
$2,003,044
@ $20.03
Significance 4

ZLAB CEO Du Ying sells 100,000 shares for $2.0M via scheduled 10b5-1 plan; stock down -11.4% in 30 days, -53.6% from 52-week high.

Du Ying executed 5 separate sales totaling 100,000 shares for $2,003,044.43 on 2026-05-13 and 2026-05-14 under a pre-arranged 10b5-1 trading plan adopted on 2025-11-11, reducing her holdings from 1.22M shares to 1.12M shares. The transaction is scheduled and non-discretionary; pricing varied significantly across tranches (from $1.74 to $20.22 per share), reflecting market conditions during the execution window. The company is unprofitable (net income $-51,016,000.00), though revenue stands at $99,611,000.00 with annual growth of +15.3%. At current price of $20.59, the stock trades -53.6% from its 52-week high of $44.34 and is down -11.4% over the prior 30 days, a sharp decline from where some of these shares were sold.

March 2026
2026-03-19 10b5-1 Plan
medium
1,731 shares
$32,733
@ $18.91
Significance 4

ZLAB director Gaynor Richard buys 1,731 shares at $18.91 as stock down 56.8% from 52-week high

Director Richard Gaynor purchased 1,731 shares at $18.91 on 2026-03-17, expanding his holdings from 54,899 to 56,630 shares. The transaction occurred at a significant discount to the 52-week high of $43.03, with the stock currently trading -56.8% from its peak and down 7.1% over the preceding 30 days. Zai Lab continues to operate at a loss with net income of $-35,963,000.00 against revenue of $116,095,000.00 in the latest quarter, though the company has demonstrated +15.3% annual revenue growth. This insider purchase by a director warrants monitoring to understand whether it reflects confidence in the business trajectory or simply opportunistic accumulation at depressed valuation levels.

2026-03-10 10b5-1 Plan
medium
Du Ying Sell
Chairperson & CEO
100,000 shares
$1,922,400
@ $19.22
Significance 6

ZLAB CEO Du Ying sold 100,000 shares for $1,922,400.00 in 2 transactions; stock down 54.8% from 52-week high.

Du Ying, the Chairperson & CEO, executed 2 separate sales totaling 100,000 shares for $1,922,400.00 on 2026-03-06 and 2026-03-09, reducing holdings from 1,064,161 to 964,161 shares. The blended average price of $19.22 reflects modest transaction prices relative to ZLAB's 52-week range of $16.30–$43.03; the current price of $19.46 sits 54.8% below the 52-week high. At the same-ticker level, Du Ying's prior 2 measurable sales (August 2025) both registered negative 90-day returns (-38.0% and -36.1%), demonstrating well-timed execution ahead of declines. The company carries negative net income of $-35,963,000.00 on quarterly revenue of $116,095,000.00, operating at a loss despite 15.3% annual revenue growth. The consecutive sales within 3 days warrant observation of broader intent given the unprofitable operational profile.

2026-03-06 10b5-1 Plan
low
Du Ying Sell
Chairperson & CEO
100,000 shares
$1,919,208
@ $19.19
Significance 3

Du Ying, then-CEO of Zai Lab, sold 100,000 shares for $1.9M under pre-arranged 10b5-1 plan

Du Ying, who held the title Chairperson & CEO at the time, executed 3 separate sales totaling 100,000 shares for $1,919,208.40 at prices ranging from $18.78 to $19.32 on 2026-03-04 and 2026-03-05. This transaction was executed under a pre-arranged 10b5-1 trading plan adopted on 2025-11-11, meaning the timing and quantities were scheduled in advance rather than discretionary. The sale reduced his holdings from 1,064,161 shares to 964,161 shares, a reduction of 100,000 shares. As a scheduled transaction under a trading plan, the filing reflects adherence to a predetermined schedule rather than a discretionary decision responsive to current market conditions.

September 2025
2025-09-12
medium
See Remarks
10,000 shares
$289,100
@ $28.91
Significance 4

Smiley Joshua L bought 10,000 shares of Zai Lab (ZLAB) at $28.91 on 2025-09-10; stock down 7.9% in 30 days, 0 of 4 prior buys well-timed at 90-day mark

Smiley Joshua L purchased 10,000 shares at $28.91, increasing his holdings by 13.1% to 86,604 shares total. The company's fundamentals show revenue of $109,977,000.00 for the latest quarter with annual growth of +49.6%, but it remains unprofitable with net income of $-40,727,000.00 (latest quarter) and negative full-year earnings. Relative to price context, the current price of $32.80 is 23.8% below the 52-week high of $43.03 and the stock is down 7.9% over the past 30 days. His prior buy timing at this ticker shows a concerning pattern: across 4 prior ZLAB purchases, 0 were well-timed at the 90-day mark, with cumulative 90-day performance including -24.0%, -12.7%, -32.6%, and -28.0%. The cross-ticker track record reinforces this pattern—an average 90-day return of -24.3% with a 0% win rate across 4 prior buys. This transaction represents continued accumulation into a stock where his own historical entry points have not materialized into gains within three months, and the company continues to run an operating loss despite revenue momentum.

August 2025
2025-08-14 10b5-1 Plan
medium
Du Ying Sell
Chairperson & CEO
96,387 shares
$3,357,842
@ $34.84
Significance 4

ZLAB CEO Du Ying sells 96,387 shares for $3,357,841.59; cross-ticker track record shows well-timed sells (52.94% rate) but same-ticker history shows poor 90d outcomes.

Du Ying executed 2 separate sales totaling 96,387 shares for $3,357,841.59 on August 12–13, 2025, reducing holdings by 15.2% from 633,349 shares to 536,962 shares post-transaction. The blended average price of $34.84 falls near the current price of $34.93, suggesting limited post-sale appreciation. Across all tickers, Du Ying's prior 20 open-market sells achieved a 52.94% well-timed rate with a 90-day average return of 4.2%—indicating a modest pattern of selling ahead of weakness. However, at this specific ticker (ZLAB), his 2 prior sells with measurable 90-day outcomes both posted gains (19.0% and 22.2%), the inverse of well-timed sales; the most recent measurable same-ticker sale on 2025-06-26 returned only 2.9% at 30 days. The company remains unprofitable (net income $-40.7M on revenue of $110.0M), though it posted strong 49.6% annual revenue growth. The timing context here is mixed: cross-ticker track record suggests competence in sell-timing, but same-ticker history at ZLAB shows the opposite pattern.

2025-08-12 10b5-1 Plan
low
Du Ying Sell
Chairperson & CEO
100,000 shares
$3,468,970
@ $34.69
Significance 3

Du Ying sold 100,000 shares ($3.5M) via scheduled 10b5-1 plan; post-sale holdings: 537.0K shares

Du Ying, who was Chairperson & CEO at the time of this filing, executed 2 separate sales totaling 100,000 shares for $3,468,970.00 on August 8 and 11, 2025, at a blended average price of $34.69. This transaction was part of a pre-arranged 10b5-1 trading plan adopted on 2024-11-20, meaning the sales were scheduled and non-discretionary rather than responsive to current market conditions. The sale reduced his holdings by 15.7%, from 637.0K shares to 537.0K shares. As a scheduled disposition under a pre-existing plan, this transaction does not convey timing-based signals about his contemporaneous views on valuation.

June 2025
2025-06-27
medium
Du Ying Sell
Chairperson & CEO
23,669 shares
$855,208
@ $36.13
Significance 5

ZLAB CEO Du Ying sold 23,669 shares at $36.13 on 2025-06-26; stock down 19.3% from 52-week high.

Du Ying's sale of 23,669 shares (23.7K shares) at $36.13 represents a 4.4% reduction in holdings at a price 19.3% below the 52-week high of $43.03. The timing is noteworthy: his prior 5 trades at ZLAB (all in May 2025) occurred near the peak, with subsequent 30-day gains of +40.6% to +50.7%, suggesting strong positioning before the recent decline. His cross-ticker track record shows 19 prior sells with a 90-day well-timed rate of 100.00%, though outcomes at ZLAB are not yet measurable at the 90-day horizon. The company is unprofitable (net income $-48.4M in the latest quarter) with strong revenue growth of +49.6% year-over-year, creating a pattern consistent with early-stage biotech selling strength into execution risk.

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