SMMT Summit Therapeutics Inc. Insider Trading

SMMT Co-CEO Zanganeh buys 3.81M shares at $13.12; stock down 28.4% in 30d, at -56.6% from 52-week high; cluster pattern with 2 other insiders in past 14 days.

Mahkam Zanganeh (Co-Chief Executive Officer) purchased 3,810,000 shares at $13.12 on 2026-06-12, increasing his holdings to 573,883,879 shares. This buy occurs amid sharply declining equity price: the stock is at $13.46 current price, down 28.4% over 30 days and 56.6% below its 52-week high of $30.98. At the same-ticker level, Zanganeh's prior four measurable trades at SMMT show mixed results (30-day range -12.2% to +20.8%; 90-day range -9.1% to +115.9%), with only 1 of 4 prior buys well-timed at the 90-day mark. The company reported $0.00 revenue (latest quarter) and net income of -$189,424,000 over the most recent full fiscal year, establishing an unprofitable operational baseline. Notably, 2 other insiders also bought within the past 14 days, creating a cluster buy pattern during a period of significant stock depreciation.

Summit Therapeutics Co-CEO Duggan buys 3,810,000 shares ($50.0M) at $13.12; stock down -56.6% from 52-week high, cluster buy pattern detected

Robert W Duggan purchased 3,810,000 shares at $13.12 on 2026-06-12, adding $50.0M to a position that now totals 573.88M shares. The purchase occurs in a sharp decline context: the stock is trading -56.6% from its 52-week high of $30.98 and down -28.4% over the past 30 days. At SMMT specifically, Duggan's prior 3 measurable trades have delivered mixed results—a recent 30-day win (20.8%) reversed into a 90-day loss (-3.7%), and a -12.2% 30-day loss extended to -9.1% at 90 days—with none of the prior trades being well-timed at the 90-day mark. The company is reporting zero revenue in the latest quarter and is unprofitable, with full-year net income at negative $189.4M. A cluster pattern is present: two other insiders also bought within the past 14 days, suggesting coordinated conviction at depressed prices. This filing merits scrutiny given the timing into a severe drawdown, the company's negative fundamentals, and Duggan's uneven track record at this specific ticker.

Robert W Duggan (Co-CEO) buys 100,000 shares of SMMT at $14.60; stock now -52.1% from 52-week high, cluster buy pattern detected.

Co-Chief Executive Officer Robert W Duggan purchased 100,000 shares at $14.60 on 2026-06-04, increasing holdings to 25.82M shares. The transaction occurred as the stock trades 52.1% below its 52-week high of $30.98 and has fallen 15.4% over the prior 30 days. At this same ticker, Duggan's 3 prior buys have shown poor timing at the 90-day mark: 0 of 3 prior purchases were well-timed, with results ranging from -12.2% to +20.8% at 30 days but consistently negative at 90 days. Two other insiders also purchased shares within the past 14 days, indicating a cluster-buy pattern. The company remains unprofitable with net income of $-189.4M over the most recent full fiscal year, though Duggan's cross-ticker track record shows an average 90-day return of +3.9% across 20 prior buys, with a 40.00% win rate.

Co-CEO Mahkam Zanganeh buys 100,000 SMMT shares at $14.60; stock down 52.1% from 52-week high despite $1.5M buy.

Mahkam Zanganeh, Co-Chief Executive Officer, purchased 100,000 shares at $14.60 on 2026-06-04, increasing his holdings from 25,724,474 to 25,824,474 shares. The stock has declined 52.1% from its 52-week high of $30.98 and is trading at $14.84, down 15.4% over the past 30 days. At the same ticker, his prior 5 buys show mixed outcomes: two trades showed 90-day gains of +115.9% and +115.3%, while the most recent buy on 2025-10-21 yielded a 90-day return of -9.1%. The company is unprofitable with a net income of $-189,424,000.00 for its most recent fiscal year and zero revenue in the latest quarter, presenting a high-risk fundamental backdrop against which this equity purchase occurs.

COO and CFO Manmeet Singh Soni bought 50,000 shares at blended average price $14.44 on 2026-06-04, adding to 3.12M share position. Stock down 52.1% from 52-week high.

Manmeet Singh Soni, serving as both COO and CFO, executed 2 separate purchases totaling 50,000 shares for $722,250.00 at average price $14.44 on 2026-06-04. The purchase increases his holdings to 3,123,603 shares. This purchase occurs as the stock trades at $14.84, down 52.1% from its 52-week high of $30.98 and down 15.4% over the prior 30 days. Soni's cross-ticker track record shows 1 prior buy against 9 prior sells, and his single prior buy at SMMT (2023-10-13) has no measurable outcome data. The company posted negative net income of $-189,424,000.00 and zero revenue in the latest quarter, indicating material operational challenges. The timing of this insider purchase against depressed valuation and company fundamentals warrants attention, though the insider's historical bias toward selling activity limits inference of strong conviction from a single buy transaction.

Co-CEO Zanganeh Mahkam buys 26,680 shares of SMMT at $18.74; stock -48.9% from 52-week high, company unprofitable with $-231.8M net income.

Zanganeh Mahkam purchased 26,680 shares valued at $499,983.20 on 2025-10-21, extending a pattern of frequent accumulation at this ticker. Across his prior 5 trades at SMMT, three identical March 2024 buys each posted 90-day returns of +115.3% to +115.9%, and two September 2025 buys achieved 30-day returns of +18.2% and +20.8%; timing pattern shows 3 of 3 prior buys were well-timed at the 90-day mark. However, the current investment context is notably challenged: the stock trades -48.9% below its 52-week high of $36.70, has declined -34.6% over 90 days, and the company reported $0.00 revenue (latest quarter) with a net loss of $-231.8M annually. A 2-insider cluster buy within the past 14 days suggests coordinated confidence, yet absent profitable operations or revenue generation, the trade occurs against a materially weakened fundamental backdrop that distinguishes it from the company's prior high-valuation environment where his March and September purchases occurred.

Director Xia Yu buys 533,617 shares of SMMT at $18.74 ($10.0M) amid cluster pattern; stock down 48.9% from high

Xia Yu, a Director, purchased 533,617 shares at $18.74 on 2025-10-21, adding $10.0M in capital to a position that now stands at 32,057,147 shares. The purchase occurred as SMMT trades 48.9% below its 52-week high of $36.70 and 90-day momentum has declined 34.6%. The stock is currently unprofitable with net income of $-231,793,000 and zero quarterly revenue, signaling the company remains in an early or struggling stage. Notably, 2 other insiders also bought within the past 14 days, creating a cluster buy pattern that warrants investor attention as multiple leadership figures are deploying capital at these depressed valuations simultaneously.

Co-CEO Duggan buys 26,680 shares at $18.74 for $500.0K, increasing SMMT holdings 53.4%; cluster of 3 insider buys in 14 days amid -34.6% 90-day decline and $-231.8M annual loss.

Robert W. Duggan, Co-Chief Executive Officer, purchased 26,680 shares at $18.74 on 2025-10-21, increasing his total holdings to 76,680 shares (a 53.4% increase from pre-transaction holdings). The purchase occurred as the stock is down 34.6% over 90 days and trades 48.9% below its 52-week high of $36.70. This transaction is part of a cluster pattern: 2 other insiders also bought within the past 14 days. Duggan's prior two purchases at SMMT on 2025-09-10 and 2025-09-11 each showed positive 30-day performance (+20.8% and +18.2% respectively), though 90-day outcomes are not yet measurable. Notably, the company is unprofitable, having reported net income of $-231.8M in its most recent full fiscal year, which adds material context to why the timing and clustering of these insider purchases warrants investor scrutiny of the strategic rationale.

Co-CEO Zanganeh buys 338,394 shares at $17.69 avg (2 txns, $6.0M) as SMMT stock falls 27.6% in 30 days from 52-week high of $36.70.

Mahkam purchased 338,394 shares across two transactions on 2025-09-10 and 2025-09-11 at a blended average price of $17.69, investing $5,984,755.92 in the open market. The purchase occurs during a sharp decline—the stock has fallen 27.6% over the past 30 days and trades 49.3% below its 52-week high of $36.70. Mahkam's same-ticker history at SMMT shows 4 prior measurable buys executed in late March and December 2023, all of which generated positive 90-day returns ranging from 113.3% to 115.9%, demonstrating a pattern of well-timed accumulation at this ticker. The company remains unprofitable with a $-565,708,000.00 net loss in its most recent fiscal year and zero quarterly revenue, yet maintains a $13.8B market cap; this buying activity by the co-CEO during a period of weakness and amid fundamental challenges represents a material capital commitment that merits close investor observation.

Co-CEO Duggan buys 338.4K shares for $6.0M at $17.69 avg amid 49.3% stock decline from 52-week high

Robert W. Duggan, Co-Chief Executive Officer, executed 2 separate purchases totaling 338.4K shares for $6.0M on September 10-11, 2025, at a blended average price of $17.69 per share. This occurs while the stock trades at $18.60, down 49.3% from its 52-week high of $36.70 and down 27.6% over the preceding 30 days, representing a period of significant share price deterioration. The company is unprofitable with a net income of -$565.7M in its latest fiscal year and zero revenue in the latest quarter, indicating material operational challenges. Duggan's cross-ticker track record shows 20 prior open-market buys with an 82.35% 90-day win rate and average 90-day return of +10.2%, establishing a pattern of execution discipline; however, this company-specific context—deep losses, zero revenue, and a severely depressed valuation after multi-month declines—is substantially different from the broader portfolio metrics and demands separate scrutiny.