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CRSP CRISPR Therapeutics AG Insider Trading

17 filings analyzed · Latest 2026-03-12
Insider buys
4
Insider sells
13
Unique insiders
7
Direction
Net selling

Historically, stocks have lagged the S&P 500 by a median ~4% over the 90 days after a high insider sell (n ≈ 9,950, 2021-2026). Past results don't predict the future. How we measure this ↗

March 2026
2026-03-12
high
Chief Executive Officer
9,798 shares
$517,334
@ $52.80
Significance 6/10

CEO Kulkarni Samarth sold 9,798 shares of CRSP at $52.80 on 2026-03-11, stock now down -36.4% from 52-week high at $48.87.

Kulkarni Samarth, CEO, sold 9,798 shares at $52.80, reducing his position by 4.0% to 235.6K shares. The sale occurred at a price 8.1% above the current market price of $48.87, and notably the stock has declined -36.4% from its 52-week high of $76.78. CRSP's fundamentals are deteriorating: the company reported -90.6% annual revenue decline with quarterly revenue of $889.0K and a net loss of $106.4M. Across his cross-ticker track record, the insider has executed 20 prior sales with a 100.00% well-timed rate at the 90-day mark (averaging -17.5% 90-day returns after sells). At CRSP specifically, his prior two measurable sales both exhibited negative 90-day returns (-22.6% and -9.7%), indicating a consistent pattern of selling before subsequent declines in this security.

January 2026
2026-01-27
medium
Chief Medical Officer
1,508 shares
$49,704
@ $32.96
Significance 4/10

CMO Patel Naimish buys inaugural 1,508 shares of CRSP at $32.96 amid company's -90.0% annual revenue decline and $-106.4M net loss.

Patel Naimish, Chief Medical Officer, purchased 1,508 shares at $32.96 on 2025-04-03, establishing an initial position in CRSP. This is notable given the company's severe financial deterioration: annual revenue growth stands at -90.0% with a latest-quarter revenue of $889.0K, and the company posted a full-year net income of $-106.4M. The buy occurs when the stock trades 29.3% below its 52-week high of $76.78, and the 90-day decline of -13.3% suggests recent downward momentum. As a first-time buyer with no prior holdings, this represents a new commitment to company stock at a significantly depressed valuation relative to recent price history, though the company's profitability crisis remains unresolved.

2026-01-26
high
Chief Financial Officer
34,972 shares
$2,104,965
@ $60.19
Significance 6/10

CRSP CFO sells 34,972 shares at $60.19 for $2.1M; holds just 6,767 post-trade amid -90.0% revenue decline and -$106.4M net loss

Prasad Raju sold 34,972 shares (83.8% of pre-transaction holdings) at $60.19 on 2026-01-22, exiting nearly the entire position and retaining only 6,767 shares worth $368,757 at the $54.65 current price. The CFO's action occurs against a backdrop of severe operational deterioration: annual revenue collapsed 90.0% to $889.0K quarterly run-rate, the company reported a $-106.4M net loss in its most recent fiscal year, and the stock has declined 28.8% from its 52-week high of $76.78. His cross-ticker track record shows 6 prior sells averaging -2.4% returns over 30 days, and at CRSP specifically he has conducted five prior sales since 2025-12-22, three executed just 16 days before this transaction. The dramatic concentration of sales in a three-week window (2025-12-22 and 2026-01-06 dates, plus this 2026-01-22 sale) combined with the near-total liquidation of his position suggests structured reductions rather than opportunistic selling, yet the company's financial deterioration provides clear contextual weight to the timing.

2026-01-22
high
Chief Executive Officer
90,000 shares
$5,166,298
@ $57.40
Significance 7/10

CEO Kulkarni sells 90,000 CRSP shares across 3 trades (Jan 20–22) for $5.2M at blended avg $57.40; holdings drop 40.1% to 134.2K shares.

Kulkarni executed 3 separate sales totaling 90,000 shares for $5,166,297.83, reducing his stake by 40.1% from 224.2K to 134.2K shares. The multi-day execution (Jan 20–22) across three distinct price points ($51.61, $52.10, $60.23) occurred in the context of the stock trading near its 52-week high at the time of the highest-priced tranche ($60.23 on Jan 22). At CRSP specifically, Kulkarni's prior 5 trades all achieved negative 90-day returns, with a 100% well-timed rate at this ticker. Fundamentals show a severely strained business model: annual revenue growth of -90.0%, latest-quarter revenue of only $889,000.00, and full-year net income of $-106,441,000.00. The CEO's substantial reduction in holdings amid deep operating losses and a dramatic revenue contraction represents a material shift in his equity exposure to the company.

2026-01-08
high
Chief Financial Officer
29,700 shares
$1,786,636
@ $60.16
Significance 6/10

CFO Prasad Raju sells 29,700 shares at $60.16 avg (81.4% of holdings); company in revenue decline with -$106.4M net loss

Prasad Raju, CFO of CRISPR Therapeutics, executed 3 separate sales totaling 29,700 shares for $1,786,635.87, reducing his holdings from 36,467 shares to 6,767 shares (an 81.4% reduction). The sales occurred at a blended average price of $60.16, which is 6.7% above the current price of $56.40 and near the 52-week high range. The timing of this substantial liquidation warrants attention given CRISPR's underlying business trajectory: the company reported revenue of $889,000.00 in the latest quarter and an annual revenue decline of -90.0% year-over-year, paired with a full-year net loss of -$106,441,000.00. While the sale price itself was not depressed relative to recent trading, the magnitude of the reduction and the company's severe revenue contraction suggest a material shift in the CFO's exposure to the stock. This is the CFO's second concentrated sell event at this ticker within two weeks, following three sales on 2025-12-22, indicating sustained reduction of personal position rather than a one-time adjustment.

December 2025
2025-12-23
high
Chief Financial Officer
10,000 shares
$559,549
@ $55.95
Significance 6/10

CRSP CFO Prasad Raju sold 10,000 shares for $559,548.74 (blended avg $55.95), reducing holdings by 59.6%

Prasad Raju, CFO of CRISPR Therapeutics, executed 3 separate sales on 2025-12-22 totaling 10,000 shares for $559,548.74, reducing his position from 16,767 to 6,767 shares. The sale occurred near the current price level ($56.46), and notably at a time when the stock is -26.5% from its 52-week high of $76.78. The company is operating in a context of significant operational challenges: Revenue contracted 90.0% year-over-year to $889,000.00 in the latest quarter, and the company generated a $-106,441,000.00 net loss, extending unprofitability through the most recent full fiscal year. A CFO disposing of nearly 60% of his holdings in a context of severe revenue contraction and sustained losses warrants investor attention to the underlying financial trajectory and management's perspective on near-term prospects.

October 2025
2025-10-20
high
Chief Executive Officer
50,895 shares
$3,456,279
@ $67.91
Significance 7/10

CRSP CEO Kulkarni sells 50,895 shares for $3.5M; 4 of 4 prior CRSP sells were well-timed; co. revenue off -90.0% YoY, $892K last qtr, unprofitable.

Samarth Kulkarni, CEO of CRSP, sold 50,895 shares at $67.91 on 2025-10-17, reducing his holdings by 16.7% to 254.2K shares. His prior trade history at CRSP shows a strong execution pattern: all 4 of 4 prior sells were well-timed at the 90-day mark, with the most recent (2025-02-19) followed by a 90-day return of -25.7%, indicating the stock declined after his sales. His cross-ticker track record also shows 100.00% well-timed rate across 20 prior sells, though with an average 90-day return of -19.3%. Against this context of demonstrated timing accuracy, the current sale occurs as CRSP faces severe operational headwinds: revenue contracted 90.0% year-over-year to just $892K in the latest quarter, net income was negative $208.5M, and the company remains unprofitable over its most recent full fiscal year. While CRSP trades near its 52-week high (only -3.7% from the peak of $76.78), the fundamental deterioration combined with his consistent pattern of selling before declines warrants investor attention to the underlying business trajectory.

August 2025
2025-08-19
high
Chief Executive Officer
13,081 shares
$760,660
@ $58.15
Significance 7/10

CRSP CEO sells 13,081 shares at $58.15; stock now $54.16 (-20.5% from 52-week high). All 5 prior CRSP sales well-timed.

Samarth Kulkarni, CRSP's CEO, sold 13,081 shares (13.1K shares) on 2025-08-18 at $58.15, reducing his stake by 5.9% to 207,004 shares (207.0K shares). The stock has since declined to $54.16 and is -20.5% from its 52-week high of $68.14, with a 30-day decline of -16.8%. Critically, all 5 of Kulkarni's prior open-market sales at CRSP were well-timed—each showing negative 90-day returns after execution—and his cross-ticker track record demonstrates a 100.00% well-timed sell rate across 20 prior sales with an average 90-day return of -18.9%. Against this backdrop of consistent prescience, the company's fundamentals are deeply troubled: annual revenue contracted -90.0% to $892,000.00 (latest quarter), net income is $-208,549,000.00 (the company is unprofitable), and market cap stands at $4,925,874,909.68. The insider's sale timing and the company's operational deterioration align as mutually reinforcing signals warrant close investor scrutiny of CRSP's near-term trajectory.

2025-08-08
high
20,000 shares
$1,140,600
@ $57.03
Significance 7/10

CRSP director Douglas A. Treco purchases 20,000 shares for $1.1M, 10x his prior 2,000-share position

Director Treco Douglas A purchased 20,000 shares at $57.03 on 2025-08-06, expanding his holdings from 2,000 to 22,000 shares—a 1000.0% increase in position size. This is a material acquisition by a board-level insider following substantial recent price momentum: the stock is at $55.00 today, down 19.3% from its 52-week high of $68.14 but up 54.4% over the past 90 days. The purchase occurred in the context of significant fundamental headwinds: CRISPR Therapeutics reported -90.0% annual revenue growth, negative full-year net income of $-208,549,000.00, and quarterly revenue of only $892,000.00, indicating the company is deeply unprofitable and contracting. A director's acquisition of this magnitude warrants investor scrutiny regarding his conviction in the near-term outlook, given the company's deteriorating financial trajectory and whether the 90-day rally presents information asymmetry into the market.

July 2025
2025-07-17
high
989,812 shares
$51,499,918
@ $52.03
Significance 6/10

Director George Simeon bought 989,812 shares of CRSP for $51.5M at $52.03 on 2025-07-16 (3 separate transactions)

George Simeon, a Director, executed three separate open-market purchases totaling 989,812 shares for $51,499,918.36, increasing his holdings by 133.7% from 740,367 to 1,730,179 shares. The cumulative investment of $51.5M at a blended average of $52.03 represents a substantial capital commitment, and the stock currently trades at $55.09, 12.2% below its 52-week high and up 27.6% over the past 30 days and 45.9% over the past 90 days. However, Simeon's historical insider trade performance across all tickers is markedly poor: his prior two open-market purchases averaged 90-day returns of -38.7%, with a 0.00% win rate, suggesting his buying has not proven predictive of forward gains. Paired with the company's severe fundamental deterioration—revenue collapsed 90.0% year-over-year to only $865.0K in the latest quarter, net income declined to -$136.0M, and the company remains unprofitable—the large share purchase warrants scrutiny as to whether it reflects strategic conviction or other considerations such as retention, governance, or capital allocation constraints.

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